Document And Entity Information [Abstract] Document And Entity Information [Abstract] Statement [Table] Statement [Line Items] Document Type Amendment Flag Document Period End Date Document Fiscal Year Focus Document Fiscal Period Focus Entity Registrant Name Entity Central Index Key Current Fiscal Year End Date Entity Filer Category Entity Common Stock, Shares Outstanding Condensed Consolidated Balance Sheets [Abstract] Assets [Abstract] ASSETS Cash and cash equivalents CASH AND CASH EQUIVALENTS, END OF PERIOD CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD Cash and Cash Equivalents, at Carrying Value, Total Marketable securities Marketable securities ACCOUNTS RECEIVABLES Accounts receivable Accounts receivable Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current, Total Assets, Current Total current assets Property and equipment, net Property, Plant and Equipment, Net, Ending Balance Property, Plant and Equipment, Net, Beginning Balance Property and equipment, net Restricted Investments, Noncurrent Long-term investment - restricted Goodwill Goodwill, Ending Balance Goodwill, Beginning Balance Goodwill, Total Other assets Other Assets, Noncurrent, Total Assets Total assets LIABILITIES AND STOCKHOLDERS' EQUITY Accounts payable Accounts Payable, Current, Total Accrued Liabilities Current Accrued liabilities Accrued Liabilities, Current, Total Total current liabilities Total current liabilities Derivative Liabilities, Noncurrent Warrants Other Liabilities, Noncurrent Other long-term liabilities Other Liabilities, Noncurrent, Total Total liabilities Total liabilities Commitments Stockholders' Equity: Common stock, $0.01 par value-125,000,000 shares authorized; 76,686,396 shares issued and 75,638,689 shares outstanding at September 30, 2010; and 68,360,067 shares issued and 67,312,360 outstanding at December 31, 2009 Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common stock, $0.01 par value - 125,000,000 shares authorized; 79,728,447 shares issued and 78,680,740 shares outstanding at March 31, 2012; and 78,165,360 shares issued and 77,117,653 shares outstanding at December 31, 2011 Common Stock, Value, Issued, Total Additional paid-in capital Additional Paid in Capital, Ending Balance Additional Paid in Capital, Beginning Balance Additional paid-in capital Treasury stock (at cost, 1,047,707 shares) Treasury stock (at cost, 1,047,707 shares) Treasury stock (at cost, 1,047,707 shares) Treasury Stock, Value, Ending Balance Treasury Stock, Value, Beginning Balance Accumulated deficit Retained Earnings (Accumulated Deficit), Ending Balance Retained Earnings (Accumulated Deficit), Beginning Balance Accumulated deficit Accumulated other comprehensive income Accumulated Other Comprehensive Income (Loss), Net of Tax, Ending Balance Accumulated Other Comprehensive Income (Loss), Net of Tax, Beginning Balance Other comprehensive loss Accumulated other comprehensive income Total stockholders' equity Balance Balance Total stockholders' equity Total liabilities and stockholders' equity Total liabilities and stockholders' equity Common stock, par value Common stock, shares authorized Common stock, shares issued Common Stock, Shares, Issued, Total Common stock, shares outstanding Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Treasury stock, at cost Treasury Stock, Shares, Ending Balance Treasury Stock, Shares, Beginning Balance Condensed Consolidated Statements Of Comprehensive Income (Loss) [Abstract] RevenuesAbstract Revenues: Historically, this has included FTE reimbursement. It also includes reimbursement of other costs that have been incurred on behalf of a partner. Research and Development Revenue Research and development Royalty Revenue Royalty Revenue, Total Royalties License fees Revenues Total Revenues COSTS AND EXPENSES: Costs and Expenses: Direct Operating Cost, Royalty Expense Cost of royalty revenues RESEARCH AND DEVELOPMENT EXPENSES Research and development Research and development General and administrative General and administrative Total costs and expenses Total costs and expenses Operating Income (Loss) Income (loss) from operations OTHER INCOME: Other Income (Expense): Investment Income Interest Interest income Gain (Loss) on Derivative Instruments, Net, Pretax Change in fair value of warrant liability Change in fair value of warrant liability Gain (Loss) on Derivative Instruments, Net, Pretax, Total Nonoperating Income (Expense) Total other income (expense), net Net income (loss) Net income/(loss) Net income (loss) Net income (loss) Basic net (loss)/income per common share Basic net income (loss) per common share Basic net (loss)/income per common share Diluted net (loss)/income per common share Diluted net income (loss) per common share Diluted net (loss) income per common share Basic weighted average common shares Basic weighted average common shares Weighted Average Number of Shares Outstanding, Basic, Total Diluted weighted average common shares Diluted weighted average common shares Weighted Average Number of Shares Outstanding, Diluted, Total Comprehensive (loss) income Net income (loss) Comprehensive income (loss) Total comprehensive income (loss) Condensed Consolidated Statements Of Cash Flows [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES: CASH FLOWS FROM OPERATING ACTIVITIES: Adjustments to reconcile net (loss)/income to net cash (used in)/provided by operating activities: Adjustments to reconcile net income/(loss) to net cash provided by/(used in) operating activities: Depreciation and amortization Depreciation, Depletion and Amortization, Nonproduction, Total Stock-based compensation expense Stock-based compensation expense Issuance of common stock to licensees. Issuance of Common Stock to Licensees Issuance of common stock to licensees Accretion (Amortization) of Discounts and Premiums, Investments Non-cash interest (income)/expense Non-cash interest (income)/expense Gain (Loss) on Disposition of Assets Net gain on sale of assets Net gain on sale of assets Gain (Loss) on Disposition of Assets, Total Changes in operating assets and liabilities: Changes in operating assets and liabilities: Accounts Receivable Accounts receivable Prepaid expenses and other assets Prepaid expenses and other assets Prepaid expenses and other assets Accounts payable and accrued liabilities Accounts payable and accrued liabilities Accounts payable and accrued liabilities Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities Total adjustments Net Cash Provided by (Used in) Operating Activities Net cash (used in)/provided by operating activities Net cash provided by/(used in) operating activities CASH FLOWS FROM INVESTING ACTIVITIES: CASH FLOWS FROM INVESTING ACTIVITIES: Purchase of marketable securities Purchase of marketable securities Purchase of marketable securities Sale of marketable securities Sale of marketable securities Sale of marketable securities Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment, Total Proceeds from Sale of Productive Assets Proceeds from sale of assets Proceeds from Sale of Productive Assets, Total Increase in restricted cash Decrease in restricted cash Decrease in restricted cash Decrease in restricted cash Increase (Decrease) in Restricted Cash, Total Net Cash Provided by (Used in) Investing Activities Net cash (used in)/provided by investing activities CASH FLOWS FROM FINANCING ACTIVITIES: CASH FLOWS FROM FINANCING ACTIVITIES: Proceeds from Issuance of Common Stock Proceeds from issuance of common stock under the Company's share-based compensation plans and warrant exercises Net cash provided by financing activities Net cash provided by financing activities NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS NET (DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS Nature of business. Nature Of Business [Abstract] Nature of Operations [Text Block] Nature Of Business Basis Of Presentation [Abstract] Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Basis Of Presentation Revenue Recognition [Abstract] Significant Accounting Policies [Text Block] Summary Of Significant Accounting Policies Revenue Recognition Collaboration agreements [abstract] Collaboration Agreements [Abstract] Collaborative Arrangement Disclosure [Text Block] Research And Development Collaborations Collaboration Agreements Fair Value Measurements [Abstract] Fair Value, Measurement Inputs, Disclosure [Text Block] Fair Value Measurements Common Stock And Warrant Liability [Abstract] Common Stock And Warrant Liability [Abstract] Common Stock And Warrant Liability [Text Block] Common Stock And Warrant Liability [Text Block] Common Stock And Warrant Liability Accrued Liabilities [Abstract] Other Liabilities Disclosure [Text Block] Accrued Liabilities Related Party Transaction [Abstract] Related Party Transactions Disclosure [Text Block] Related Party Transaction Accounting For Stock-Based Compensation [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Accounting For Stock-Based Compensation Income (Loss) Per Common Share [Abstract] Earnings Per Share [Text Block] Income (Loss) Per Common Share Subsequent Events [Abstract] Subsequent Events [Text Subsequent Events