Document and Entity Information [Abstract] ASSETS Assets [Abstract] Current Assets: Assets, Current [Abstract] Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Marketable securities Available-for-sale Securities, Debt Securities, Current Accounts receivable, net of allowance for doubtful accounts of $430 and $339, respectively Accounts Receivable, Net, Current Allowance for doubtful accounts receivable Allowance for Doubtful Accounts Receivable, Current Inventories, net Inventory, Net Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Total current assets Assets, Current, Total Total current assets Investments Certificates of Deposit, at Carrying Value Property and equipment, net Property, Plant and Equipment, Net Intangible assets, net Finite-Lived Intangible Assets, Net Other assets Other Assets, Noncurrent TOTAL ASSETS Assets, Total TOTAL ASSETS LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities and Equity [Abstract] Current Liabilities: Liabilities, Current [Abstract] Accounts payable and other accrued obligations Accounts Payable and Other Accrued Liabilities Accrued compensation and related expenses Employee-related Liabilities, Current Deferred revenue Deferred Revenue, Current Common stock warrant liability Derivative Instruments and Hedges, Liabilities Accrued Drug Development Costs Accrued drug development costs Carrying value as of the balance sheet date of obligations incurred through that date and payable for drug development costs. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Total current liabilities Liabilities, Current, Total Total current liabilities Capital lease obligations Capital Lease Obligations, Noncurrent Deferred revenue and other credits--less current portion Deferred Revenue and Credits, Noncurrent Contingent Obligations Related to Acquisition Zevalin related contingent obligations This element represents the amount of any change, including any differences arising upon settlement, recognized during the reporting period in the value of an asset or assets, arising from an item of contingent consideration, recognized in a business combination. Total liabilities Liabilities, Total Total liabilities Commitments and contingencies Commitments and Contingencies Stockholders' Equity: Stockholders' Equity Attributable to Parent [Abstract] Preferred stock, $0.001 par value; 5,000,000 shares authorized: Preferred Stock, Number of Shares, Par Value and Other Disclosures [Abstract] Preferred stock, par value Preferred Stock, Par or Stated Value Per Share Preferred stock, shares authorized Preferred Stock, Shares Authorized Statement [Table] Class of Stock [Axis] Class of Stock [Domain] Preferred Stock [Member] Series B junior participating preferred stock Statement [Line Items] Preferred stock value Preferred Stock, Value, Issued Preferred stock, shares issued Preferred Stock, Shares Issued Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Series E convertible preferred stock Preferred Stock Liquidation Value Preferred stock, liquidation value Preferred stock, liquidation value Common stock, $0.001 par value--175,000,000 shares authorized; 57,403,724 and 51,459,284 issued and outstanding at September 30, 2011 and December 31, 2010, respectively Common Stock, Value, Issued Common stock, par value Common Stock, Par or Stated Value Per Share Common stock, shares authorized Common Stock, Shares Authorized Common stock, shares issued Common Stock, Shares, Issued Common stock, shares outstanding Common Stock, Shares, Outstanding Additional paid-in capital Additional Paid in Capital Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated deficit Retained Earnings (Accumulated Deficit) Less: Treasury stock at cost; 353,055 shares at September 30, 2011 Treasury Stock, Value Less: Treasury stock at cost; 353,055 shares at September 30, 2011 Total stockholders' equity Stockholders' Equity Attributable to Parent, Total Total stockholders' equity TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities and Equity, Total TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY Revenues: Revenue, Net [Abstract] Product sales, net Sales Revenue, Goods, Net License and Contract Revenue License and contract revenue Revenue from licensing fees. Licensing revenue is consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Total revenues Revenue, Net, Total Total revenues Operating costs and expenses: Costs and Expenses [Abstract] Cost of product sales (excludes amortization of purchased intangible assets) Cost of Goods Sold Selling, general and administrative Selling, General and Administrative Expense Research and development Research and Development Expense Amortization of purchased intangibles Amortization of Intangible Assets Total operating costs and expenses Costs and Expenses, Total Total operating costs and expenses Income (loss) from operations Operating Income (Loss) Income (loss) from operations Change in fair value of common stock warrant liability Gain (Loss) on Derivative Instruments, Net, Pretax Other income (loss), net Other Nonoperating Income (Expense) Income (loss) before provision for income taxes Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Extraordinary Items, Noncontrolling Interest Income (loss) before provision for income taxes Provision for income taxes Income Tax Expense (Benefit) Provision for income taxes Net income (loss) Net Income (Loss) Attributable to Parent Net income (loss) Net income (loss) per share: Earnings Per Share [Abstract] Basic Earnings Per Share, Basic Diluted Earnings Per Share, Diluted Weighted average shares outstanding: Weighted Average Number of Shares Outstanding, Diluted [Abstract] Basic Weighted Average Number of Shares Outstanding, Basic Diluted Weighted Average Number of Shares Outstanding, Diluted Cash Flows From Operating Activities: Net Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Amortization of deferred revenue Recognition of Deferred Revenue Amortization of deferred revenue Depreciation and amortization Depreciation, Depletion and Amortization Stock-based compensation Share-based Compensation Change in fair value of common stock warrant liability Fair Value of Common Stock Issued in Connection with Asset Acquisition Fair value of common stock issued in connection with asset acquisition Fair value of common stock issued in connection with asset acquisition Provision for bad debt Provision for Doubtful Accounts Loss on disposal of assets Gain (Loss) on Disposition of Assets Loss on disposal of assets Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Accounts receivable, net Increase (Decrease) in Accounts Receivable Accounts receivable, net Inventories, net Increase (Decrease) in Inventories Inventories, net Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other assets Accounts payable and other accrued obligations Increase (Decrease) in Other Accounts Payable and Accrued Liabilities Accrued compensation and related expenses Increase (Decrease) in Employee Related Liabilities Increase Decrease in Accrued Drug Development Costs Accrued drug development costs The increase (decrease) during the reporting period in the aggregate amount of obligations related to drug development costs. Increase Decrease in Landlord Contributions to Tenant Improvements Landlord contributions to tenant improvements Landlord contributions to tenant improvements Increase Decrease in Deferred Revenue and Other Credits Deferred revenue and other credits The increase (decrease) during the reporting period in the aggregate amount of deferred revenue and other credits. Net cash provided by (used in) operating activities Net Cash Provided by (Used in) Operating Activities Net cash provided by (used in) operating activities Cash Flows From Investing Activities: Net Cash Provided by (Used in) Investing Activities [Abstract] Maturities of marketable securities Proceeds from Sale and Maturity of Marketable Securities Purchases of marketable securities Payments to Acquire Available-for-sale Securities, Debt Purchases of marketable securities Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Purchases of available for sale securities Payments to Acquire Available-for-sale Securities Purchases of available for sale securities Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities Net cash used in investing activities Cash Flows From Financing Activities: Net Cash Provided by (Used in) Financing Activities [Abstract] Proceeds from issuance of common stock from stock option exercises Proceeds from Stock Options Exercised Proceeds from issuance of common stock from warrant exercises Proceeds from Warrant Exercises Proceeds from Contributions to Espp Proceeds from contributions to ESPP Proceeds from contributions to ESPP Proceeds from contributions to ESPP Payments to acquire treasury stock Payments for Repurchase of Common Stock Payments to acquire treasury stock Repayment of capital leases Repayments of Long-term Capital Lease Obligations Repayment of capital leases Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Net increase (decrease) in cash and cash equivalents Cash and Cash Equivalents, Period Increase (Decrease) Net increase (decrease) in cash and cash equivalents Cash and cash equivalents--beginning of period Cash and cash equivalents--end of period Supplemental Disclosure of Cash Flow Information: Supplemental Cash Flow Information [Abstract] Conversion of preferred stock to common stock Conversion of Stock, Amount Converted Common stock issued for Targent milestones Stock Issued Targent Milestone Included in Other Assets and Accrued Liabilities Targent milestones included in intangible assets and accrued liabilities Carrying amount as of the balance sheet date of amounts accrued for milestones. Business and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Business and Basis of Presentation [Abstract] Business and Basis of Presentation [Abstract] Cash, Cash Equivalents and Marketable Securities Cash and Cash Equivalents Disclosure [Text Block] Cash, Cash Equivalents and Marketable Securities [Abstract] Cash, Cash Equivalents and Marketable Securities [Abstract] Fair Value Measurements Fair Value Disclosures [Text Block] Fair Value Measurements [Abstract] Fair Value Measurements [Abstract] Intangible Assets Intangible Assets Disclosure [Text Block] Intangible Assets [Abstract] Intangible Assets [Abstract] Inventories Inventory Disclosure [Text Block] Inventories [Abstract] Inventories [Abstract] Accounts payable and accrued obligations Accounts Payable and Accrued Liabilities Disclosure [Text Block] Accounts payable and accrued obligations [Abstract] Accounts payable and accrued obligations [Abstract] Income Taxes Income Tax Disclosure [Text Block] Income Taxes [Abstract] Income Taxes [Abstract] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies [Abstract] Commitments and Contingencies [Abstract] Stockholder's Equity Stockholders' Equity Note Disclosure [Text Block] Stockholder's Equity [Abstract] Stockholder's Equity [Abstract] Long-Term Retention and Management Incentive Plan Compensation and Employee Benefit Plans [Text Block] Long-Term Retention and Management Incentive Plan [Abstract] Long-Term Retention and Management Incentive Plan [Abstract] Deferred Compensation Plan Compensation Related Costs, General [Text Block] Deferred Compensation Plan [Abstract] Deferred Compensation Plan [Abstract] Amendment Flag Current Fiscal Year End Date Document Period End Date Document Type Entity Central Index Key Entity Common Stock, Shares Outstanding Entity Current Reporting Status Entity Filer Category Entity Registrant Name Entity Voluntary Filers Entity Well-known Seasoned Issuer Entity Public Float Document Fiscal Period Focus Document Fiscal Year Focus Condensed Consolidated Balance Sheets [Abstract] Condensed Consolidated Statements of Operations [Abstract] Condensed Consolidated Statements of Cash Flows [Abstract]